Mouse IL-3 R alpha / CD123 Protein, His Tag (SPR verified) ILA-M52H4-100UG from ACROBiosystems

Supplier Images

SDS PAGE URL

Mouse IL-3 R alpha, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Supplier Page from
ACROBiosystems for
Mouse IL-3 R alpha / CD123 Protein, His Tag (SPR verified)

Description

Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily.

This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3.

The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells